Biochemistry

Adenine aminohydiolase H 2 O ---- ► NH 3 Adenine он ЪК С --- N + I if || HC ^ / C x N N H Hypoxanthine Then, hypoxanthine is oxidized to xanthine, which is oxidized to uric acid in the presence of water by the enzyme xanthine oxidase. Uric Acid Hypoxanthin (ketoform) Xanthine (ketoform) With deamination of guanine, the formation occurs even faster than with deamination of adenine. When the amino group is cleaved from is formed immediately, and then uric acid is formed. of uric acid guanine, xanthine Guanine Xanthine OH Guanine n ZV N deaminase I Г ч -H,O,NH 3 N НО N 1 н Uric acid is the end product of the purine bases metabolism in the human body. 180