Biochemistry

Schematically deamination can be represented as follows: a) Reduction +2H R-CH-COOH -> R - CH - COOH + NH 3 I -NH 3 I nh 2 h Amino acid Saturated acid b) Hydrolytic +H 2 O R-CH-COOH -> R - CH - COOH + NH 3 I -NH 3 I nh 2 oh Amino acid Hydroxyacid c) oxidative +1/2 O 2 R-CH-COOH -► R-C-COOH + NH 3 -NH 3 nh 2 Amino acid II О Keto acid Intramolecular R - CH - COOH -> R - CH = CH - COOH + NH 3 I -NH 3 nh 2 Amino acid Unsaturated fatty acid Oxidative deamination is divided into two stages. Oxidase R-CH-COOH -> R-C-COOH + NH 3 I -2H || nh 2 nh +H 2 O R-C-COOH -> R-C-COOH + NH 3 II ~NH 3 || NH О 165