Biochemistry

Figure 2.4 - Schematic representation of the three-dimensional structure of myoglobin The shape of the protein molecules can be different: from spherical to filiform', on this basis, proteins are divided into globular and fibrillar (filiform). In globular - the tertiary structure is characterized by a fairly dense packing of the chain in the form of a coil. The formation of a specific folding of a given protein is a cooperative process based on various types of chemical interactions. Schematically they are shown in Figure 2.5. The main role in this is played by hydrophobic interactions arising between nonpolar amino acid residues. Most hydrophobic groups are located inside the globule, and hydrophilic (polar) amino acid residues are localized on the outer surface. These polar groups are hydrated, which contributes to good protein solubility. Figure 2.5 - Types of chemical interactions that stabilize the structure of the protein 55