Biochemistry

The latter interacts with ADP, with the formation of A TP and pyruvic acid (PVC): COOH COOH H — c — O~PO 3 H 2 II CH 2 Phosphoenolpyruvate pyruvate kinase ' _ + ADP ------------- * C — OH + ATP ---------------- II CH 2 Pyruvate (pyruvic acid) COOH COOH | C — OH 7 — II — * c = o 1 CH 2 CH 3 Enolpyruvate Pyruvate If by the time of pyruvate formation a sufficient amount of oxygen will not be supplied to the tissue, the PVC will reduce until lactate (lactic acid) with the participation of reduced NAD (NADH 2 ). CH 3 1 + nadh 2 CH 3 c = o ---------- > CHOH -NAD 1 1 COOH COOH Pyruvate Lactate (lactic acid) Under anaerobic conditions, 85% of lactate is reduced to glycogen, and 15% is oxidized to CO 2 and H 2 O. Thus, lactate is the end product of anaerobic glucose oxidation. Under aerobic conditions, lactate is converted to pyruvate again or is used for glucose biosynthesis in the liver. This process takes place in the cytoplasm, where all glycolysis enzymes are located. With the active work of the muscles they accumulate a lot of lactic acid, which causes their fatigue. To restore the performance of the muscles, it is necessary to release them from lactic acid, which is achieved by breeding it into the blood, with which it enters the liver. So, in aerobic conditions, lactic acid in the process of 225