Biochemistry

СН 2 ОН Н /J, HPhoiphoglucomutaseH Glucose-6-phosphate Glucose-lphosphate н «сн,он І21/0-Р0 3 Н 2 н он + ( Glycogen )„_] Figure 11.3 - Phosphorilithic breakdown of glycogen In the tissues of the organs (including the liver), the breakdown of glucose occurs in two ways', anaerobic (with insufficient oxygen in the cells) and aerobic (proceeds only in the presence of oxygen). Anaerobic oxidation of substrates is the simplest form of formation and accumulation of energy in the phosphate bonds of ATP; in the evolutionary way of development, it is earlier way and was originated in an oxygen-free environment. Higher animals and humans are facultative anaerobic, that is, organisms that can function under aerobic and anaerobic conditions. However, the stage of aerobic cleavage, regardless of the presence of oxygen, is preceded by anaerobic decomposition. 219