Biochemistry

D- gluconic and D- galactonic acids (uronic acids) are formed when the aldehyde group at the C-l position is converted to a carboxylic acid. The phosphorylated form of D- gluconic acid is an important intermediate product of carbohydrate metabolism. From the oxidation of the sixth carbon atom from D- glucose , D- glucuronic acid is formed, from D- galactose - D- galacturonic acid. но — c — H HO — C — H H — C — OH COOH COOH (acyclic form) (cyclic form) D -galacturonic acid Uronic acids are biological compounds that make up polysaccharides. So, D- glucuronic acid is part of the polysaccharides of connective tissue, xylans, gums, blood glucoproteins . In its free state, it performs an important protective function - interacts with toxic substances formed in the large intestine from amino acids ; in this case, esters are formed, which are excreted from the body with urine. Similarly, with the help of glucuronic acid, some medicinal substances are neutralized and excreted from the body . Galacturonic acid is part of pectin and other polysaccharides, a- g uluronic and D- mannuronic acids are contained in the brown algae polysaccharide - alginic acid . C-H CH,OH CH,OH 1 H — с — он H 1 -c- 1 -OH c=o 1 1 HO -C-H +2H > HO 1 -C- 1 -H >2H HQ - -C-H 1 1 H - C-OH H -C-OH H - -C-OH 1 1 H -C-OH H 1 -C-OH 1 H - -C-OH 1 I CH,OH CH,OH CH,OH D -glucose D- sorbitol D -fructose 137